Friday, May 13, 2011

Drawing Figures

Two of my favorite figures in the 4th edition of Intermediate Physics for Medicine and Biology are Fig. 7.13 (the extracellular potential produced by an action potential along a nerve axon) and Fig. 8.14 (the magnetic field produced by the same axon). John Wikswo and I prepared these figures when I was in graduate school at Vanderbilt University.
Fig. 7.13 of Intermediate Physics for Medicine and Biology, 4th edition. The exterior potential calculated using the method of Clark and Plonsey.
Fig. 7.13. The exterior potential calculated using the method of Clark and Plonsey.
From Intermediate Physics for Medicine and Biology, 4th edition.
Fig. 8.14 of Intermediate Physics for Medicine and Biology, 4th edition. A three-dimensional plot of the magnetic field around the crayfish axon.
Fig. 8.14. A three-dimensional plot of the magnetic field around the crayfish axon.
From Intermediate Physics for Medicine and Biology, 4th edition.
Soon after entering graduate school in 1982, I took a class taught by John based on Russ Hobbie’s first edition of Intermediate Physics for Medicine and Biology. Clearly, the book had a significant influence on my subsequent career. (I remember the bright yellow cover of the first edition: my office is probably one of the few places outside of Minnesota where all four editions of the book sit proudly, side-by-side, on a bookshelf.) When preparing the second edition, Russ added a chapter on biomagnetism, and asked John to contribute a figure showing the magnetic field produced by an axon. Of course, this is just the sort of work graduate students are good for, and I was given the task of preparing the figure (actually two figures, as we decided to make a similar figure for the extracellular potential). This was not a big job, because I already had access to the computer code that my friend Jim Woosley had written for his master’s thesis, and which I used when preparing our paper “The Magnetic Field of a Single Axon: A Volume Conductor Model,” (Woosley, Roth, and Wikswo, 1985, Mathematical Biosciences, Volume 76, Pages 1–36).

In the mid-1980s, three-dimensional graphics programs were not as common as they are now, but we had one and I was able to create the figure. What we didn’t have was a publication-quality printer or software to prepare and manipulate figures. Therefore, once I had the plots created, they went to the drafting room to be finished. John usually had one or more undergraduates hired for the sole task of preparing figures. I don’t remember exactly who worked on the two figures for the 2nd edition, but it may have been David Barach, son of Vanderbilt physics professor John Barach. The daftsman’s job was to retrace the figure, thereby providing a higher quality appearance than a dot-matrix printer could provide. As I recall, his job was also to remove hidden lines (I don’t think that our 3-d graphics program was “smart” enough to remove hidden lines on its own). He also labeled all the axes using some really neat rub-on letters that John was able to purchase in both Roman and Greek fonts (note the “μ” in μV in Fig. 7.13). I remember David working on figures at a large, slanted drafting table, using very high quality, vellum-like paper. He had rulers, triangles, and “French curves” of all types. First the drawing was done in pencil, and then traced with black ink. Once finished, additional copies were made using photography by a center in the Vanderbilt Medical School dedicated to such work. Before Photoshop, Powerpoint, and other such programs, that is the way figures were prepared. John had a policy that all graduate students had to get some experience at the drafting table, which I didn’t mind at all. At the risk of sounding like a Luddite who is nostalgic for the days of buggy whips, I think those figures have a little more personality and visual appeal than computer-generated figures drawn today.

The figures appeared in the second edition of Russ’s book, and have continued on through subsequent editions (including the 4th edition, on which I have the high honor of becoming a coauthor). Figures like that required much time and expense to prepare, and are difficult to edit. But my, it was more fun to really “draw” those figures than it is to churn out figures using graphics software.

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