tag:blogger.com,1999:blog-9045015217135885587.post4324375712425872527..comments2024-03-27T04:05:09.556-04:00Comments on Intermediate Physics for Medicine and Biology: Optical Magnetic Detection of Single-Neuron Action Potentials using Quantum Defects in DiamondIntermediate Physics for Medicine and Biologyhttp://www.blogger.com/profile/11077661160486900345noreply@blogger.comBlogger2125tag:blogger.com,1999:blog-9045015217135885587.post-71972173845189538512016-12-23T02:42:43.189-05:002016-12-23T02:42:43.189-05:00I'm the senior author on the paper you nicely ...I'm the senior author on the paper you nicely summarize. Thank you for your insightful comments and technology comparison, with which I largely agree. A few comments: (i) the NV-diamond magnetic sensing technique is still in the early stages of development as a tool for neuroscience, with the primary challenge being improving the magnetic field sensitivity, as you point out; (ii) we are currently implementing 2D magnetic imaging, with micron-scale resolution, in analogy with what we have already done for biological systems with patterns of static magnetic fields (see http://walsworth.physics.harvard.edu/publications/2013_LeSage_Nature.pdf); and (iii) our technique does not necessarily require specific placement of the sample in 2D on the diamond chip. Thanks again.Ron Walsworthhttp://walsworth.physics.harvard.edu/index.htmlnoreply@blogger.comtag:blogger.com,1999:blog-9045015217135885587.post-4235346086354485362016-12-22T08:26:01.588-05:002016-12-22T08:26:01.588-05:00Brad - Analyze the cost. I expect that a very low-...Brad - Analyze the cost. I expect that a very low-noise current-to-voltage converter and a toroid could be built for a few hundred dollars. That said, I like the idea of not having to encircle the nerve.John Wikswohttps://www.blogger.com/profile/03311654844196046614noreply@blogger.com